Journal of Medical Physics and Biophysics Simulations

About Journal

Advancements in computational science, simulation technology, and quantitative modelling have significantly reshaped the landscape of modern medical research and clinical practice. Medical physics and biophysics, once limited to static measurements and laboratory calculations, now draw heavily on dynamic simulations, data-intensive modelling, and algorithm-driven approaches that support diagnosis, treatment planning, and biological insight. The Journal of Medical Physics & Biophysics Simulations has been established to promote the publication of high-quality, peer-reviewed research at the intersection of physics, biology, and computation in healthcare.

This journal provides a focused platform for original research, technical developments, and applied studies involving the use of physical and mathematical models in biological systems and medical applications. It recognises that simulation methods are becoming central to innovation in radiotherapy, imaging, biomechanics, drug delivery, systems biology, and other medically relevant domains. As healthcare continues to benefit from precise modelling of physiological and pathological processes, this journal aims to support the dissemination of studies that improve both theoretical understanding and clinical outcomes.

The Journal of Medical Physics & Biophysics Simulations invites contributions from researchers, medical physicists, engineers, clinicians, computational biologists, and applied mathematicians. It supports interdisciplinary work that reflects the growing collaboration between physical sciences, computational methods, and medical research. The journal’s focus is on studies that use simulation and modelling as core components of their methodology or analysis, especially in relation to patient care, device design, diagnostics, and biological mechanism exploration.

Areas of interest include, but are not limited to, the following:

• Radiation therapy planning and dose modelling
• Computational simulation of biological tissues and organs
• Radiological imaging simulations (MRI, CT, PET, SPECT)
• Monte Carlo simulations for radiation transport and dosimetry
• Biomechanical modelling of tissues, bones, and joints
• Fluid dynamics modelling in cardiovascular and respiratory systems
• Electrophysiological simulations and cardiac modelling
• Thermal modelling in hyperthermia and ablation therapies
• Mathematical models in tumour growth and cancer treatment planning
• Multiscale modelling in systems biology
• Simulation of drug delivery pathways and pharmacokinetics
• In silico trials and virtual patient modelling
• Machine learning applied to medical physics simulations
• Numerical methods for solving physical equations in biological systems

The journal welcomes original research articles that demonstrate methodological advancement, clinical relevance, or significant improvements in computational performance or simulation fidelity. Research may be theoretical, algorithmic, or applied, but it must be clearly linked to a biomedical or clinical context. The journal values clear articulation of models, reproducible methods, and detailed descriptions of simulation parameters and validation techniques.

Review articles are also accepted and should aim to summarise state-of-the-art developments in specific subfields. Such reviews must be analytical, well-referenced, and educational in tone. They should offer a structured overview of techniques, comparisons of modelling approaches, or emerging trends in simulation-based medical research.

Technical notes describing software tools, simulation platforms, or new computational frameworks are encouraged, provided they are rigorously tested and well-documented. These may include user-case descriptions, benchmark comparisons, or performance evaluations.

Authors may also submit clinical application studies where simulation techniques have been applied in treatment planning, device prototyping, or image-guided procedures. Manuscripts should clearly describe how simulation supported clinical decision-making, improved workflow, or enhanced treatment precision.

All submitted manuscripts are subject to double-blind peer review. Each submission is evaluated by reviewers with expertise in computational physics, biomedical engineering, or the specific clinical application. Reviewers assess scientific accuracy, modelling transparency, relevance to medical physics or biophysics, and clarity of presentation. Authors receive constructive feedback and may be invited to revise their work before final acceptance.

The Journal of Medical Physics & Biophysics Simulations publishes a range of article types:

• Original research articles
• Review articles
• Technical and computational method notes
• Validation studies and benchmarking papers
• Application reports and clinical implementation case studies
• Simulation-based training and educational models
• Letters discussing previously published simulation work

Submissions must be written in English and conform to the journal’s formatting and referencing standards. Authors are advised to consult the Author Guidelines before preparing their manuscript. All references cited in the text must be listed at the end of the manuscript. The journal accepts citations in APA style. Authors must ensure accuracy and consistency in referencing.

Authors must ensure that their work meets appropriate ethical standards. Manuscripts involving simulated patient data, retrospective clinical validation, or imaging from patient records must include a statement of ethical approval or exemption. Patient privacy must be protected in all figures and descriptions.

The journal encourages transparency and reproducibility. Where feasible, authors are encouraged to include simulation code, computational scripts, or supplementary materials that allow others to reproduce key results. Authors may use repositories for software sharing and data hosting and should include relevant access information in their manuscript.

The Journal of Medical Physics & Biophysics Simulations accepts global submissions. It recognises that simulation research may vary in scale, focus, and available infrastructure depending on institutional or geographic context. The journal supports submissions from research laboratories, clinical physics departments, academic groups, and collaborative consortia.

An Article Processing Charge will be levied upon acceptance of the manuscript. Full details will be communicated to the corresponding author following peer review and editorial approval.

This journal is committed to advancing the role of simulations in improving medical practice and biological understanding. As virtual modelling becomes more integrated into diagnostics, treatment, and research, the Journal of Medical Physics & Biophysics Simulations will serve as a credible and specialised platform for sharing these developments with the wider scientific and clinical community.