Aim & Scope
The World Journal of Molecular Medicine (ISSN: 3065-5196) is devoted to publishing research that enhances understanding of molecular mechanisms underpinning human physiology, disease processes, and therapeutic interventions. The journal's aim is to serve as a comprehensive resource for scientists, clinicians, and scholars who seek to explore and expand the molecular foundation of biomedical science and clinical medicine.
Our scope encompasses a wide spectrum of research within the molecular and cellular biology disciplines, with a special focus on how these fundamental mechanisms translate into clinical relevance. This includes both basic and applied research that contributes to diagnostics, therapeutics, and disease prevention strategies.
We strongly encourage submissions that examine the genetic, biochemical, and cellular events involved in both normal biological processes and pathological conditions. The journal also supports studies that explore the functional consequences of genetic mutations, post-translational modifications, and molecular signaling pathways.
Molecular Medicine and Translational Research
The journal promotes the advancement of molecular medicine as a bridge between laboratory discoveries and clinical practice. We support original studies and reviews that demonstrate how insights at the DNA, RNA, and protein levels can be applied to develop diagnostic tests, therapeutic strategies, and personalized treatment approaches. Research related to molecular biomarkers, gene editing technologies, pharmacogenetics, and molecular imaging is of particular interest.
Genomic and Epigenetic Studies
We welcome research that investigates gene expression profiles, chromatin remodeling, epigenetic regulation, DNA methylation, histone modifications, and their implications in human diseases. Studies focusing on the role of long non-coding RNAs, microRNAs, and other regulatory elements are highly valued, especially when they provide mechanistic insight or clinical applicability.
Cellular and Molecular Pathways
The journal covers work that examines molecular mechanisms in cell cycle regulation, apoptosis, autophagy, oxidative stress, and mitochondrial dysfunction. We aim to highlight research that deciphers intracellular and intercellular signaling cascades and how dysregulation contributes to disease onset or progression. These include but are not limited to cancer biology, metabolic disorders, immune response modulation, and neurodegenerative diseases.
Infectious Disease Mechanisms
We support the publication of molecular research on viral, bacterial, fungal, and parasitic infections. This includes studies of pathogen-host interactions, molecular mechanisms of immune evasion, viral genome replication, and antimicrobial resistance. Submissions involving vaccine development, antiviral agents, and diagnostic markers from a molecular perspective are also welcomed.
Targeted Therapeutics and Drug Development
Another central area within the journal’s scope involves the discovery and development of molecularly targeted therapies. This includes drug screening studies, identification of molecular drug targets, small molecule inhibitors, monoclonal antibodies, RNA-based therapies, and gene therapy. Emphasis is placed on research that shows translational value from laboratory findings to clinical application.
Molecular Diagnostics and Biomarker Discovery
We publish research focused on the development and validation of molecular diagnostic tools, including polymerase chain reaction (PCR)-based assays, next-generation sequencing (NGS), CRISPR-based detection systems, and molecular imaging technologies. Studies identifying new diagnostic, prognostic, or predictive biomarkers for various diseases are especially encouraged.
Precision Medicine and Individualized Treatment
The journal is interested in studies that contribute to the growing field of precision medicine. This includes work that evaluates how individual genetic variations can inform treatment decisions, optimize therapeutic efficacy, and reduce adverse effects. Research addressing population-specific genomic data and their use in clinical settings aligns well with this scope.
Technological Innovations in Molecular Research
We welcome submissions that discuss innovative technologies that enhance molecular investigations. Topics may include new laboratory methods, data analysis tools, bioinformatics algorithms, imaging platforms, or computational models that support the understanding and manipulation of molecular systems.
Interdisciplinary and Collaborative Research
Given the complexity of molecular systems, we encourage submissions that reflect collaborative, cross-disciplinary efforts. Integrating insights from molecular biology, biochemistry, clinical medicine, pharmacology, biotechnology, and computational biology often leads to more comprehensive understanding and impactful research outcomes.
The World Journal of Molecular Medicine provides an academic environment where molecular discoveries are not only shared but also contextualized within the broader spectrum of human health and disease. By publishing scientifically rigorous and clinically relevant content, the journal aims to promote the responsible application of molecular knowledge in patient care, drug development, and public health.
