Aim & Scope
The Journal of Precision Medicine and Genomic Therapeutics is dedicated to advancing the science and clinical application of personalised medicine through the integration of genomic knowledge, molecular diagnostics, and individualised therapeutic strategies. The journal aims to serve as a platform for researchers, clinicians, pharmacologists, data scientists, and translational specialists working at the intersection of genetics and clinical care.
Its core objective is to promote research that moves beyond generalised treatment frameworks by exploring how genomic and molecular information can guide disease prevention, diagnosis, and therapy. The journal recognises precision medicine as a dynamic and evolving field that draws upon genetic variation, bioinformatics, environmental context, and real-time health data to support more targeted and effective clinical decisions.
The Journal of Precision Medicine and Genomic Therapeutics supports work that builds bridges between laboratory science, therapeutic innovation, and applied clinical practice. It encourages a multidisciplinary approach, integrating expertise from molecular biology, pharmacogenomics, bioengineering, health technology, and systems medicine. The journal also recognises the ethical, legal, and social dimensions of personalised care and invites contributions that explore these themes in detail.
Through the publication of original research, reviews, case studies, and translational evaluations, the journal seeks to contribute to the global progress of personalised healthcare in both specialised and primary care settings.
Scope
The journal welcomes a broad range of submissions related to the scientific, technological, and clinical implementation of precision medicine. Authors are encouraged to submit manuscripts that reflect high-quality research, methodological transparency, and relevance to the goals of personalised treatment.
The journal accepts content across the following key focus areas:
1. Genomic Profiling and Clinical Application
Manuscripts describing the use of genomic data to inform medical decisions are central to the journal. Topics include:
- Whole genome and exome sequencing in clinical diagnosis
- Variant interpretation and reporting frameworks
- Genotype-phenotype correlation studies
- Population-specific genomic data and rare variant analysis
- Genetic risk prediction models for non-communicable diseases
- Screening strategies informed by hereditary predisposition
- Integration of family history into genomic evaluation
Submissions should include discussion on clinical interpretation and potential pathways to implementation.
2. Molecular and Pharmacogenomic Therapeutics
The journal supports studies on the design and validation of therapies based on genetic and molecular profiles. These include:
- Pharmacogenomic testing for drug response and toxicity
- Genotype-guided drug development and selection
- RNA-based therapeutics including siRNA and antisense oligonucleotides
- CRISPR and other gene-editing techniques with therapeutic intent
- Molecular pathway targeting in oncology and rare disease treatment
- Resistance mechanisms in targeted therapies
- Combination therapy strategies guided by molecular diagnostics
Manuscripts must demonstrate scientific rigour and relevance to clinical outcomes.
3. Precision Oncology
A key focus of the journal is the integration of precision strategies in cancer care. Topics of interest include:
- Tumour mutational profiling for treatment planning
- Liquid biopsy and circulating tumour DNA applications
- Companion diagnostics for targeted drug approval
- Genomic stratification in clinical trials
- Biomarker development and validation
- Real-world evidence on personalised oncology practices
Authors should clearly present both laboratory findings and clinical application pathways.
4. Bioinformatics and Clinical Data Integration
Submissions are invited in the area of computational biology, decision support, and the integration of large-scale biological data. Topics include:
- Development of algorithms for variant interpretation
- Predictive modelling using multi-omics data
- Clinical decision support systems based on genetic markers
- Data architecture for personalised care workflows
- Electronic health record integration with genomic testing platforms
- Visualisation tools for clinician and patient use
- Machine learning in treatment response prediction
Authors should provide sufficient methodological detail and describe usability in clinical contexts.
5. Translational Research and Clinical Implementation
The journal publishes manuscripts that focus on the movement of precision science from research into clinical care. This includes:
- Pilot implementation of genomic tools in clinical settings
- Workflow design for pharmacogenomic testing in hospitals
- Clinical utility and cost-effectiveness studies
- Barriers to access and clinician education in precision medicine
- Use of real-world evidence in policy and clinical guideline development
- Population-level deployment of screening programmes
- Evaluation of turnaround time, reporting standards, and patient outcomes
Authors should include discussion on feasibility, limitations, and potential for wider adoption.
6. Ethical, Legal, and Policy Perspectives
The journal invites critical examination of the ethical dimensions and regulatory frameworks shaping precision medicine. Topics include:
- Informed consent models in genomic testing
- Data privacy and the use of genetic information in clinical settings
- Equity and access to personalised medicine tools
- Policy frameworks for genomic research in underrepresented populations
- Return of incidental findings and secondary data use
- Commercialisation of testing platforms and transparency standards
Submissions in this category may include empirical studies or theoretical analysis.
7. Educational Tools and Institutional Capacity Building
Authors may submit manuscripts related to training programmes, interdisciplinary education, or the development of institutional frameworks to support precision medicine.
Topics include:
- Medical school curricula incorporating genomics and bioinformatics
- Continuing education for healthcare providers
- Development of interdisciplinary teams for personalised care
- Case-based teaching models
- Institutional strategies for clinical genomics adoption
Submissions should include outcomes assessment or detailed programme description.
The journal is open to submissions from institutions across the globe. Authors working in varied health systems, including public, private, and community-based programmes, are encouraged to share experiences, outcomes, and adaptations of precision approaches. Studies that highlight implementation in low-resource or diverse population contexts are especially valued.
All manuscripts must be original, clearly written, and properly cited. All references cited in the text must be listed at the end of the manuscript. The journal accepts citations in APA style. Authors must ensure accuracy and consistency in referencing.
By supporting the documentation and dissemination of research in personalised care, the Journal of Precision Medicine and Genomic Therapeutics aims to strengthen the global dialogue on patient-centred treatment and foster ongoing innovation at the molecular and systemic levels of healthcare.
