The Role of Medicinal Herbs in Endothelial Tissue and their Function in Veins Health
Abstract:
The inflammatory control of veins is crucial for vascular health, with endothelium being a key organ in the physiology of blood vessels. The endothelium regulates the function of the vascular barrier, coagulation pathways, and motor tone, performing essential roles during infections and injuries due to its wide distribution throughout the body and constant interaction with circulating blood. One of the diseases that most affect endothelial function is the cardiovascular disease. This occurs due to decreased inflammatory control through metabolic changes, mainly in the hormone insulin. Some clinical studies have already demonstrated that combinations of certain ingredients from natural sources can improve endothelial function due to their synergistic effects when administered together, enhancing both inflammatory control and the production of free radicals in the endothelium, such as PPARs expression, nuclear factor kappa- beta (NF-kβ), tumor necrose factor alpha (TNF-α) and interleukin - 6 (IL-6) activity, and superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) activity respectively. In this review, we evaluated several studies on how medicinal plants can help in vascular treatments, separately or collectively, especially when it comes to diseases that affect the veins and the possibility of future treatment.
