Abstract: Journal of Comparative Medicine Research Reviews and Reports

Abstract:
Introduction Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) is one of the most common and clinically relevant causes of euvolemic hyponatremia, especially in the hospitalized setting, with the incidence in selected cohorts ranging as high as 30% [1]. While medications, malignancies, and CNS or pulmonary conditions are commonly implicated, ketamine represents an under-appreciated yet emerging pharmacologic predisposing factor. We describe and discuss a clinical case of ketamine-induced SIADH (a case of acute). We review epide miological data, diagnostic criteria, pathophysiologic mechanisms, differential diagnoses, scoring systems, ther apeutic strategies, and outcomes of patients in an evidence-based and comprehensive manner based on current literature.