Physical Therapy and Rehabilitation of a Patient with Hereditary Sensorimotor Polyneuropathy Charcot-Marie-Tooth Type 1A - Case Report
Abstract:
Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common hereditary demyelinating peripheral neuropathy, characterized by progressive distal muscle weakness, sensory loss, and functional impairment. Despite its prevalence, evidence-based rehabilitation protocols remain limited, particularly for adults with long-standing disease. This case report presents a 49-year-old female with genetically confirmed CMT1A who completed a 20-day individualized rehabilitation program combining physical therapy and kinesitherapy. Pre- and post-intervention 2 assessments included Manual Muscle Testing (MMT), Timed Up and Go (TUG), 6-Minute Walk Test (6MWT), and Visual Analog Scale (VAS) for pain. Following treatment, the patient demonstrated measurable improvements: upper and lower limb strength increased by 0.5 MMT grades, TUG time decreased by 2.4 seconds, 6MWT distance increased by 40 meters, and pain reduced from 6/10 to 3/10. These results highlight the potential of intensive, short-term, multimodal rehabilitation to improve muscle strength, balance, endurance, and pain in CMT1A patients.
