Abstract: Journal of Clinical and Biomedical Advances

Abstract:
Memory replay is a process mainly taking place in the hippocampus where it is mediated by Sharp Wave Ripples (SWRs). Memory replay leads to memory consolidation, and it can be seen in both sleep and awake states and furthermore it can unfold in the forward or reverse direction. The reverse memory replay is thought to underly the process of reinforcement learning. Further investigations are needed regarding the exact underlying mechanisms of SWRs and memory replay, because they could be targets for innovative therapeutic interventions.