Abstract: Journal of Infectious Diseases and Viruses Research

Abstract:
The debate over mandatory vaccination has gained renewed attention in the context of the COVID-19 pandemic, raising questions about the balance between individual freedom and public health. This article explores the circumstances under which mandatory vaccination may be justified, drawing on historical examples such as the eradication of smallpox and polio. Key factors in the decision-making process, including disease mortality, transmissibility, and vaccine effectiveness, are discussed. The article also examines the ethical implications, economic impact, and the importance of public trust in the implementation of mandatory vaccination policies. A systematic approach involving regression analysis, animal models, human epidemiological data, and historical evaluations is proposed to guide decisions about mandatory vaccination. By considering these multifaceted aspects, this article aims to provide a comprehensive framework for evaluating when and how mandatory vaccination should be enforced.