Abstract:
Background: Low back pain (LBP) is a common disorder, with high repercussion in quality of life and a significant economic burden. Etiology is multifactorial and diagnosis focused on triggering causes. First line therapy usually starts with conservative approaches. As minimally invasive technique, percutaneous oxygen-ozone injections, due to its analgesic and anti-inflammatory effect, represent an integrative treatment. Objective: Aim of this literature review is to explore the possible role and utility of ultrasound performing paravertebral oxygen-ozone therapy out of clinical settings. Results: Imaging-guided procedures compared with anatomical landmarks techniques, showed better therapeutic performance with higher impact on pain reduction and lower age-related variability. The anatomical view reduces the risk, improves safety and efficacy. Conclusions: Systematic reviews and meta-analyses in the literature justify ozone use in pain medicine. Evidence is low mainly for the lack of studies with adequate and consistent methodologies.