Abstract: Journal of Gynecology Obstetrics and Mother Health

Abstract:
Neuroendocrine carcinoma breast emerges as an infrequently discerned, primary, low grade to intermediate grade neoplasm implicating mammary gland parenchyma. Neoplasm represents with histological features pre-eminently (>90%) indicative of neuroendocrine cellular differentiation, tumour configuration and immunohistochemistry pertaining to neuroendocrine markers, as necessitated for appropriate tumour categorization. Nomenclature as carcinoid tumour or atypical carcinoid tumour of breast is not recommended. Initially categorized as tumours with neuroendocrine differentiation, the current World Health Organization (WHO) classification categorizes the lesion as neuroendocrine neoplasm, inclusive of designations as neuroendocrine tumour (NET) or small cell and large cell neuroendocrine carcinoma. Nevertheless, a formal grading system applicable to the neoplasm is absent.