Abstract: Science Set Journal of Medical and Clinical Case Studies

Abstract:
Toxoplasmosis is a globally relevant infection, and accurate detection of Toxoplasma IgM antibodies is essential for early diagnosis and clinical decision-making. This study assessed the performance of four widely used serological methods in detecting Toxoplasma IgM in a large patient cohort. Between January 1, 2024, and December 31, 2024, a total of 7,607 patients were tested at GeniusLab. Four methods—BKAccess2, ELISA, Roche E801, and Minividas Blu— were used for confirmation. Minividas Blu demonstrated the highest accuracy, confirming 99.5% of positive cases, while ELISA showed a 90% confirmation rate. Roche E801 had the highest rate of false-positive results. These f indings highlight variability in detection methods and underscore the importance of selecting reliable diagnostic tools.