Efficacy and Safety of Terbinafine in the Treatment of Tinea Corporis: A Clinical Knowledge Review
Abstract:
Case: A male in his late 20s presented with well-demarcated erythematous plaques, pruritus, and scaling on the trunk, clinically diagnosed as tinea corporis. The patient had a history of similar infections and had been unsuccessfully treated with topical antifungals.
Treatment and outcome: The patient was administered oral terbinafine, 250 mg twice daily, for a duration of four weeks. Adjunctive topical antifungal agents (Myconazole ointment) were also used. Regular follow-up was conducted to assess clinical response and monitor for potential adverse effects on liver function. Treatment resulted in complete resolution of lesions, with no recurrence observed during the follow-up period. The patient did not report any side effects or concerns regarding the treatment.
Discussion: This case highlights the efficacy of terbinafine in managing tinea corporis at the prescribed dose. The twice-daily 250 mg regimen proved effective in achieving favorable outcomes within a short treatment period. This case supports terbinafine as a first-line treatment for tinea corporis, particularly in cases requiring systemic therapy.
Conclusion: Oral terbinafine remains a cornerstone in the management of tinea corporis, providing high efficacy with excellent tolerability. This case underscores the importance of individualized treatment regimens to optimize outcomes in dermatophyte infections.
