Effects of Haemodialysis on Some Haematological Parameters in Chronic Kidney Disease Patients Attending a Dialysis Centre in Southern Nigeria
Abstract:
Chronic Kidney Disease (CKD) is frequently associated with haematological abnormalities, and haemodial ysis may influence these parameters. This study evaluated pre and post-haemodialysis changes in some hae matological parameters among CKD patients attending a dialysis centre in Southern Nigeria. A comparative cross-sectional study was conducted among 163 CKD patients undergoing maintenance haemodialysis. Venous blood samples were collected before and after haemodialysis for the assessment of some haematological indi ces using standard protocols. Data were analysed using appropriate statistical tests at a significance level of p < 0.05. Post-haemodialysis findings showed a slight, non-significant increase in total white blood cell count, while neutrophils, lymphocytes, and monocytes demonstrated non-significant reductions. Basophil percentage increased significantly following haemodialysis (p < 0.05). Haemoglobin and haematocrit levels increased sig nificantly after haemodialysis, from 9.79 ± 1.52 to 10.56 ± 1.74 g/dL and from 29.30 ± 5.09 to 32.33 ± 5.36%, respectively (p < 0.05). Platelet count showed a non-significant increase. Haemodialysis significantly improves haemoglobin and haematocrit levels in CKD patients. Regular monitoring of these parameters is essential for effective clinical management of CKD patients undergoing haemodialysis.
