Abstract: Journal of Psychiatry and Neurochemistry Research

Abstract:
Blood being one of the most important connective tissues, hematological study was done after isolating blood sample from Bt cry protein fed rats thereby determining the effect of the protein if any. Blood cell count was done by using Neubauer’s Haemocytometer slide and it was observed the total count of erythrocytes gradually decreased as compared to the control. This can be either by, degrading RBCs or by, causing an infection. Study on differential count of leukocytes showed that there was an increase in the neutrophil, eosinophil and monocyte count in blood along with a drastic decline in basophil count as compared with the control. This might again be an indication of certain infection in the toxin fed rats as neutrophil, eosinophil & monocyte acts as a first responder to infection. Further, the PBMCs (Peripheral Blood flow Mononuclear Cells) showed that normal morphology of monocytes and lymphocytes were distorted. The cells were found to be ruptured and the degraded cell membrane had certain black dots that are yet to be inferred.