Correlation of Lumbosacral Radiography, Calcium, Phosphate, and Vitamin D Levels with Bone Mass Density (BMD) in Pediatric Patient
Abstract:
Background: Dual X-ray absorptiometry (DXA) still represents the "gold standard" for the diagnosis of osteoporosis, meanwhile the availability of DXA has not been widely distributed, especially in minute areas. This study compares bone mass density (BMD) with a lumbosacral radiograph and laboratory parameters, that may help the early detection of osteoporosis.
Purpose of Research: This study analyzes the lumbosacral radiographs and the correlation between calcium, phosphate, and vitamin D levels with bone density in pediatric patients at Saiful Anwar Hospital, Malang, East Java.
Research Method and Sample: This is an analytical observational retrospective study that examines pediatric patients undergoing BMD, lumbosacral radiography, and laboratory tests on their calcium, phosphate, and vitamin D levels at Saiful Anwar Hospital, Malang, over the past year.
Result and Discussion: Based on the findings of this study, there is a significant correlation between lumbosacral radiograph and BMD with a p-value of <0.005, sensitivity of 90%, and specificity of 96%; and a significant correlation between vitamin D and bone density, with a p-value <0.005. The availability of vitamin D is more sensitive to detected osteoporosis rather than calcium dan phosphate blood level.
Conclusion: Excellent sensitivity and specificity of lumbosacral radiographs may become a modality for the early detection of osteoporosis in children in minute health facilities. In addition to lumbosacral radiographs, vitamin D can also act as a parameter for the early detection of osteoporosis in pediatric patients and is more accurate if the examination is combined.
