Correlation of Hysteroscopy with Histopathology Findings in Various Age Group: Our experience in Secondary Care Hospital
Abstract:
Structural abnormalities of the uterus such as polyps, fibroids, and endometrial hyperplasia are major con tributors to abnormal uterine bleeding (AUB), infertility, and reproductive dysfunction. However, diagnostic limitations of ultrasound and blind curettage often delay accurate diagnosis. Hysteroscopy, in combination with histopathology, offers both direct visualization and tissue confirmation, yet few studies have analyzed age-specific pathological pat- terns using this approach. This retrospective study evaluated 797 women who underwent diagnostic hysteroscopy and endometrial biopsy at a secondary care hospital in Oman from 2018 to 2022. Patients were grouped by age: reproductive (15–40 years), premenopausal (41–52), and postmeno pausal (≥53). Clinical indications, ultrasonographic findings, hysteroscopic observations, and histopathology reports were analyzed. Pearson’s Chi-square tests were used to assess correlations. AUB was the most common indication (43.9%), followed by infertility (29.5%). Hysteroscopy identified endometrial polyps in 40.4% of cases, particularly in pre- and postmenopausal groups. Histopathology revealed proliferative endometrium (41.7%) and secretory endometrium (19.7%) as the most common findings, predominantly in younger women. Significant correlations were observed between hysteroscopic, ultrasonographic, and histopathological find ings (p < 0.001). Hysteroscopy with histopathological confirmation is a reliable diagnostic approach for intra uterine pathologies, offering age-specific diagnostic clarity. Its integration into routine gynecological assess ment, especially in secondary care settings, may lead to more personalized and effective clinical management.
