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Comparative Analysis of Antibacterial Effect of Cranberry Tea vs Cranberry Fruit on Gram-Negative Bacteria Using Agar Well Method

Abstract:
The word "cranberry" originated from the Pilgrims, who called it "craneberry" because the small, pink blossoms seen in spring resemble the head and bill of a Sandhill crane. Cranberries come from North America, where they are native to the cooler regions of the continent. They grow naturally in acidic bogs, marshes, and wetlands in areas such as the northeastern United States and eastern Canada. Cranberries are also cultivated in other parts of the world with suitable climates, including parts of Europe and Asia. There are two known species of cranberry those are: the American cranberry (Vaccinium macrocarpon) and the European cranberry (V. oxycoccos). For centuries, Cranberry (Vaccinium macrocarpon) has served dual purposes both as a food and as medicine. Cranberry's efficacy in treating urinary infections is widely acknowledged and supported by empirical evidence. This natural remedy has been consistently utilized to address urinary tract infections, showcasing its therapeutic potential and longstanding reputation as a reliable treatment option. Cranberries contain proanthocyanidins that interfere with the ability of bacteria to grow, specifically Gram-negative bacteria. These compounds may prevent the bacteria from sticking to the urinary tract walls, making it more difficult for them to cause infections such as urinary tract infections (UTIs). Additionally, cranberries contain other bioactive compounds that may have antibacterial properties, further contributing to their potential effects against Gram-negative bacteria. In this experimental study, we employed the agar well technique to investigate the impact of various cranberry formulations on Gram-negative bacteria. Our approach involved examining multiple types of cranberries to distinguish their comparative efficacy in inhibiting the growth of Gram-negative bacterial strains. By analyzing the size and extent of inhibition zones produced by different cranberry forms, our aim was to identify the most effective form for combating Gram-negative bacterial infections.