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Characterization of Transcatheter Aortic Valve Replacement (TAVR) in Adults Undergoing Intervention Over Eight Years

Abstract:
Introduction: Aortic stenosis is the most common valve disease in the adult population. Many of the patients with this pathology are not candidates for surgical replacement of the aortic valve. Transcatheter aortic valve replacement (TAVR) is considered a less invasive treatment for patients with high surgical risk aortic stenosis.

Method: We carried out a retrospection based on the analysis of the clinical records of the CEDIMAT patients treated in the period from January 2015 to December 2022. To extract the information, we used a 14-itemquestionnaire including the EUROSCORE II; we evaluated echocardiographic and functional class changes before and after the procedure.

Results: With a sample of 11 patients, the study revealed echocardiographic changes in the valve area from0.7 ± 0.1 cm2 to 1.8 ± 0.4 cm2, mean gradient of 49.3 ± 9.3 mmHg at 6 .41 ± 2.19 mmHg, maximum velocity of4.1 ± 0.4 m/s to 1.7 ± 0.3 m/s, and ejection fraction of 59.6 ± 7.1% to 60.9 ± 5.1%. Pre-procedure, 54.5% of the patients studied were found to be in functional class II, 36.4% in functional class III, and 9.1% in functional class IV. After performing the procedure, the patients became asymptomatic or with mild symptoms, with90.9% in functional class I and 9.1% in functional class II.

Discussion: After the procedure, the patients significantly reduced their symptoms, with a great improvement in their echocardiographic findings and few post-procedure complications.