Can you Create Low Molecular Weight Pharmacologically Active Substances and Maintain Mental Function Normal? Yes, we Can
Abstract:
The author has made the chemistry of 1-hydroxyindole, a fictional chemical substance that did not actually exist, a reality. He developed a general method for synthesizing 1-hydroxyindole, and the resulting 1-hydroxy-N-acyl tryptamine derivative is a2-blocker that has the effects of eliminating active oxygen, improving blood circulation, promoting metabolism, and anti-aging, and reduces the “itching” caused by atopic dermatitis. It also has the effect of inhibiting platelet aggregation, and has been found to have the potential to be a stronger dementia treat ment than cilostazol. He also discovered a nucleophilic substitution reaction that leads to serotonin and melatonin derivatives, and found that melatonin tribromo derivatives can activate osteoblasts and become a treatment for osteoporosis. Furthermore, by incorporating the 1-hydroxyindole structure into the chemical structures of phyto alexins, β-carbolines, ergot alkaloids, yohimbine, etc., it has become possible to create new pharmacologically active substances that add the above effects to the pharmacological actions of the original substances. We also demonstrated that 1-methoxyindole derivatives function as anticancer agents in our daily diet and are useful for maintaining health. Furthermore, we found that acetaldehyde produced from ethanol by oxidation with active oxygen reacts with the neurotransmitter serotonin in the presence of nicotine and KF and is easily converted into neurotoxins such as 1H-azepino[5,4,3-cd]indole and/or tryptamine-4,5-dione, revealing that refraining from smoking and drinking is important for maintaining healthy physical and mental functions and suppressing aging.
