Abstract: Science Set Journal of Medical and Clinical Case Studies

Abstract:
Pericardial effusion is a potentially fatal condition with varied presentations, often obscured in patients with complex medical histories. We report a patient with ESRD on dialysis, AML, and CHF who presented with hypoxia and dyspnea, initially presumed to be in CHF exacerbation. However, clear lung fields and lack of edema prompted further evaluation. An elevated D-dimer led to CT angiography, revealing a large pericardial effusion. After platelet transfusion, urgent pericardiocentesis drained 800 cc of hemorrhagic fluid. Despite intervention, the patient deteriorated and passed away. This case underscores the need for diagnostic vigilance in patients with multiple comorbidities.