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Overcoming the Abyss: Effective Management of a Gram-Negative Microbial Corneal Ulcer with Melting and Impending Perforation in a Contact Lens Wearer

Abstract:
Background: To present the management of a compelling case of gram-negative microbial corneal ulcer, accompanied by corneal melting and impending perforation in a 39-year-old female contact lens wearer.

Methods: Corneal scrapings for culture were taken. Owing to a strong suspicion of Pseudomonas being the offending agent, IV Ceftazidime 2gr x3 was incorporated into the regimen alongside with intense topical antibiotic drops.

Results: On a 5-day follow-up corneal melting subsided, the hypopyon had minimized, and the anterior chamber reaction had downgraded and cultures yielded Pseudomonas.

Conclusions: Post-discharge, she was followed in outpatient, scheduled for DALK