Abstract: Journal of Medical Images and Medical Education Research

Abstract:
Alopecia universalis is the most severe form of alopecia areata and is often associated with autoimmune mech anisms, chronic infections, and immune dysregulation. This case report presents a 7-year-old boy who pro gressed from alopecia areata to alopecia universalis within 15 days. Initial treatment with corticosteroids and biotin worsened his condition. Upon request, an integrative evaluation was performed, including lymphocyte typing and herpesvirus serologies. Findings indicated EBV reactivation and immune system hyporeactivity. Treatment with an anti-inflammatory diet, micro-immunotherapy, and micronutrition resulted in full remission of symptoms, including regrowth of facial and eyelash hair. This case emphasizes the importance of integrative immunological approaches in pediatric alopecia, especially when conventional treatments are insufficient or lead to adverse effects.