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A Novel Theoretical Framework for Early Myopia Detection Using Structured Light and Modulation Transfer Function Analysis

Abstract:
Purpose: To address the growing global prevalence of myopia by introducing a cost-effective, portable framework for early detection, with a focus on pediatric applications and underserved communities.

Method: The proposed method combines structured light projection, Modulation Transfer Function (MTF) analysis, and liquid lens adjustment to enable precise, non-invasive measurement of refractive error and axial elongation. Theoretical foundations, key equations, and simulation-based validations are presented.

Results: Simulations demonstrate the feasibility of MTF-based refractive error analysis and axial length estimation using liquid lens adjustments. The proposed approach is sensitive to variations in refractive error and provides accurate estimations of myopia-related parameters.

Conclusion: The framework has the potential to transform myopia screening by offering a scalable and accessible solution for early diagnosis and monitoring. Future work will focus on experimental validation and hardware optimization to translate this concept into a deployable device. Translational Relevance: This method represents a significant step toward democratizing access to precision ophthalmic diagnostics, particularly in resource-limited settings, and has implications for reducing the global burden of myopia.